PeTA 
PeTA focuses its attention on the four areas in which the largest numbers of animals suffer the most intensely for the longest periods of time: on factory farms, in laboratories, in the clothing trade, and in the entertainment industry. They also work on a variety of other issues, including the cruel killing of beavers, birds and other "pests," and the abuse of backyard dogs.
Humane Farming Association
HFA's goals are to protect farm animals from cruelty, to protect the public from the dangerous misuse of antibiotics, hormones, and other chemicals used on factory farms, and to protect the environment from the impacts of industrialized animal factories. HFA's National Veal Boycott continues to be the single most successful campaign ever conducted against factory farming. Achieving an unprecedented drop of 70% in the sale of drugged, anemic, and tortured baby calves, HFA's groundbreaking investigations have resulted in the first-ever felony convictions of veal industry leaders.
Earth Island Institute
Life on earth is imperiled by human degradation of the biosphere. Earth Island Institute develops and supports projects that counteract threats to the biological and cultural diversity that sustain the environment. Through education and activism, these projects promote the conservation, preservation, and restoration of the Earth.
Friends of Animals
Works to cultivate a respectful view of nonhuman animals, free-living and domestic. Our goal is to free animals from cruelty and institutionalized exploitation around the world.
Earthsave/Earthsave International
EarthSave educates people about the powerful effects our food choices have on the environment, our health and all life on Earth, and encourages a shift toward a healthy, plant-based diet.
GREY2K USA Education Fund
Dedicated to the welfare of greyhound dogs, spreading the word about greyhounds through educational outreach, paid advertisements, special events and informational exhibits.
Animal Sanctuary Foundation
Educates the public about cruelty to animals via a Powerpoint presentation on three screens on their truck, Black Beauty.
Animal People
The leading independent newspaper providing original investigative coverage of animal protection worldwide.
Education & Action for Animals
We are a diverse group of very ordinary people who view animals as fellow beings, deserving of respect and compassion, not as products, tools, or commodities for human use. Our mission is to inform the public about and take action against the many forms of animal exploitation present in modern society, but especially in Delaware.
The Humane Society of the United States/HSUS Disaster Relief Fund (formerly The Ark Trust)
The Humane Society of the United States is singularly devoted to raising public awareness of animal issues by encouraging and honoring the major news and entertainment media. They believe the media can and does make a difference, and strive to activate the awesome power of the media to influence public opinion and promote positive behavior that will ultimately lead to a more humane and animal conscious society.
FARM
Farm Animal Reform Movement is a public-interest organization advocating plant-based (vegan) diets to save animals, protect the environment, and improve health.
Animal Shelter, Inc.
Providing rescue and other programs, shelter, and adoption.
Animal’s Voice Magazine
An award-winning, independent, networking source of recent media coverage, timely information, and an incalculable volume of resources for animals and their defenders.
In Defense of Animals
An international animal protection organization dedicated to ending the exploitation and abuse of animals by raising the status of animals beyond that of mere property, and by defending their rights, welfare and habitat. IDA’s efforts include educational events, cruelty investigations, boycotts, grassroots activism, and hands-on rescue through our sanctuaries in Mississippi and Cameroon, Africa.
SPCA of Texas
The Society of the Prevention of Cruelty to Animals of Texas is the leading animal welfare agency in North Texas with two shelters and three spay/neuter clinics, and serves as an active resource center providing an array of programs and services that bring people and animals together to enrich each others' lives.
NEADS
Trains and provides rescued dogs and donated puppies to assist people who are deaf or physically disabled in leading more independent lives at work, at home and at school.
Animal Rescues & Sanctuaries
Humane America Animal Foundation
Have you ever wondered what you could do to help make the world a better place for millions of homeless pets? Well we did, and that's why we started 1-800-Save-A-Pet.com, a pet adoption charity that helps shelters, humane societies, SPCA's, and pet rescue groups advertise their homeless pets to adopters for free.
Greyhound Friends
Greyhound Friends Inc., is dedicated to saving racetrack greyhounds and placing them in responsible loving homes.
Noah’s Wish
Rescues and shelters animals during disasters throughout the United States.
Center for Captive Chimpanzee Care
A Sanctuary where rescued chimpanzees can live out their lives without the threat of ever returning to a laboratory.
Second Chance Animal Shelter
Provides temporary shelter to stray, abandoned, and surrendered animals for the purpose of finding permanent suitable new homes, including assistance and financial aid to prevent overpopulation through spaying and neutering programs.
Marine Mammal Conservancy
Located in the Upper Keys of Florida, The Marine Mammal Conservancy is operated exclusively for charitable, scientific, and educational purposes, including but not limited to the research, rescue, rehabilitation, release and/or retirement of marine mammals, and to operate a facility which serves as a "halfway house" to bring marine mammals from unsuitable, artificial, or overcrowded public display situations and/or stranding situations, and then to reintroduce such marine mammals back into their natural environments; or, for those unsuited to release, a quiet retirement.
Maple Farm Sanctuary
A farm animal sanctuary providing lifelong homes for abused, abandoned and unwanted farmed animals while promoting veganism and respect for all life through public information.
Catskill Animal Sanctuary
Provides a safe and loving haven for abused and abandoned horses and farm animals, while raising awareness of the treatment of these animals and its impact on all of us and our environment.
Yankee Golden Retriever Rescue
Dedicated to providing veterinary care, comprehensive evaluation and adoptive homes to Golden Retrievers who are abandoned, mistreated, neglected or left in pounds throughout the six New England states (Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Vermont).